The Two-Headed Serpent is an epic, explosive, adventure-filled journey around the world set in the Pulp Cthulhu of the 1930s. The heroes face the sinister machinations of an ancient race of monsters determined to rule a world that was once theirs.

Working for Caducée, a charitable medical organization, the heroes will plunder a lost temple in the forests of Bolivia, take on the mafia in New York, face a deadly epidemic in the jungles of North Borneo, uncover the machinations of a strange cult during the Dust Bowl in Oklahoma, infiltrate enemy territory in a waking volcano in Iceland, battle the results of hideous experiments conducted in the Congo, set out in search of a powerful ancient artifact in the streets of Calcutta, brave the deadly perils of Snake Island, and travel to the lost continent of Mu for a desperate battle to save humanity from slavery and annihilation!

Discover nine adrenaline-fueled adventures, tips for the Keeper, beautiful color maps, and all the clues for players.

This supplement is intended for use with the roleplaying game Call of Cthulhu 7th Edition and/or the Pulp Cthulhu version, both available separately. At least one copy of the Keeper's Handbook is required to play.